If you’re an NFL betting enthusiast that likes to make Over/Under total wagers based on the game’s final combined score, then you’re going to be treated to a great O/U pick when Tom Brady and the red-hot New England Patriots hit the road to take on Derek Anderson and the mostly woeful Buffalo Bills.

If you want to know whether the Over or Under is the right pick when the explosive Pats and offensively-challenged Bills throw down on Monday Night Football, then let’s get to my expert O/U pick right now.

Monday Night Football: New England Patriots at Buffalo Bills

Game Information

🏈: Monday Night Football: New England Patriots (5-2) at Buffalo Bills (2-5)
⏰: Monday, October 29, 2018, 8:15 PM ET
🏟️: New Era Field, Orchard Park, NY
📺: ESPN, DTV: 206
🎰: New England Patriots -14 -105 | -1100 | O 44½ -110

New England Patriots

Tom Brady and the New England Patriots held off a late comeback attempt to get past Chicago 38-31 in a thrilling affair that ended when Chicago’s Hail Mary attempt on the game’s final play came up one yard short.

“You hold your breath when I saw him jump up and catch it,” Brady said. “I didn’t have the angle on the goal line. He was getting close to the end zone. They were pushing and we were pushing. It was probably a half yard or a yard, pretty close. Good for us to hold them out.”

Monday Night Football: New England Patriots at Buffalo Bills_Tom-Brady (1)

Tom Brady completed 25 of 36 passes for 277 yards with three TD passes and one interception in the win as the game’s final score played well over the 48.5-point total.

Running back James White had two TD receptions in the win while totaling 97 combined rushing and receiving yards while wide receiver Josh Gordon added four catches for 100 yards. New England picked off Bears quarterback Mitch Trubisky twice and recovered two fumbles in the win while playing Over their O/U total for the third straight game.

Buffalo Bills

The Bills brought in veteran quarterback Derek Anderson to steady their wavering ship, but it didn’t matter as the Bills took an emphatic 37-5 loss on the chin against Indianapolis on Sunday. Anderson, who Buffalo signed off the street less than two weeks ago because former starter Nathan Peterman is completely awful, played in place of injured starter Josh Allen and promptly went 20 for 31 for 175 yards with no touchdowns and three interceptions. Buffalo’s defense gave up four TD passes to Andrew Luck in the loss while getting shut out for three of the game’s four quarters while the final score played Under the 43.5-point total.

Monday Night Football:  New England Patriots at Buffalo Bills_Josh-Allen (1)

“I just have to be better with the ball, have better awareness,” Anderson said. “I’m not going to pout about it. I expect more from myself. I came here to help this team win football games.”

The Bills lost star running back LeSean McCoy to a head injury on the second play of the game and he’s likely to sit out in Week 8 as he deals with the league’s concussion protocol. Buffalo has played Under their O/U total in five straight games.

Expert Pick and Prediction

I know the Bills can barely score the ball as they average a pathetic1.6 points per game, but Tom Brady and the Patriots can put points on the board in a hurry (30.6 ppg). Besides, with both of these teams giving up a generous 25.0 points per game or more, I like the Over to narrowly play out in this week 8 AFC East divisional battle.

Monday Night Football:  New England Patriots at Buffalo Bills Winner

The Over is 4-0 in New England’s last four games following an SU win and 5-2 in their last seven games of field turf. The Over is also 7-2 in Buffalo’s last 9 Monday Night Football games and 14-4 in the Bills last 18 home games. Last but not least, the Over is 5-2 in the last seven meetings between these two teams. I like New England to cover the spread and the Over to narrowly play out in this one YouWager NFL betting enthusiasts!

Predicted Score Patriots 38 Bills 10