Are Carson Wentz and the Philadelphia Eagles locks to beat Matt Ryan and the Atlanta Falcons in their NFL Week 1 matchup in the City of Brotherly Love?

Could the revamped and revitalized Cleveland Browns cover the chalk – or beat – the Pittsburgh Steelers in their season-opening AFC North divisional duel?

Will the Week 1 meeting between the Houston Texans and New England Patriots produce another ‘Instant Classic’ like last season’s matchup between the two AFC Super Bowl hopefuls?

If you’re an NFL gridiron gaming enthusiast that is looking to get your 2018 NFL regular season betting campaign off to a positive start and you’re looking for some expert betting insight that could help you in your quest to cash in early and often this coming season, then you’ve come to the right place!

This look at all of the Week 1 odds and main betting trends surrounding each matchup will help you do just that. Now, let’s get started.

Week 1

Thursday, Sept. 6, 2018

Atlanta Falcons at Philadelphia Eagles (-4, 46.5)

The Eagles had their toughest postseason game against Atlanta in the divisional round a year ago, before escaping with a narrow 10-6 win.

  • Falcons are 7-1 ATS in their last 8 Thursday games.
  • Falcons are 4-1 ATS in their last 5 games in September.
  • Falcons are 2-6 ATS in their last 8 road games.
  • Eagles are 10-2 ATS in their last 12 games on grass.
  • Eagles are 4-1 ATS in their last 5 games in Week 1.
  • Eagles are 7-2 ATS in their last 9 home games.
  • Home team is 5-1 ATS in their last 6 meetings.

Sunday, Sept. 9, 2018

Pittsburgh Steelers at Cleveland Browns (+5.5, 46.5)

While the road team in this division rivalry has gone 3-1-1 ATS in the last five meetings, the revamped Browns just have the look of a team that isn’t going to roll over – for anyone in 2018!

  • Steelers are 2-5-1 ATS in their last 8 vs. AFC North.
  • Steelers are 1-5 ATS in their last 6 vs. AFC.
  • Steelers are 1-6 ATS in their last 7 games overall.
  • Steelers are 2-5 ATS in their last 7 games in Week 1.

San Francisco 49ers at Minnesota Vikings (-5.5, 46)

The new-look Niners will be competitive, but Minnesota has the look of a Super Bowl favorite from where I’m sitting.

  • 49ers are 6-1 ATS in their last 7 games in Week 1.
  • 49ers are 4-1 ATS in their last 5 road games
  • Vikings are 7-1 ATS in their last 8 games in September.
  • Vikings are 42-19 ATS in their last 61 games overall.

Cincinnati Bengals at Indianapolis Colts (-3.5, 46)

Andrew Luck is back!

Bengals are 5-0 ATS in their last 5 vs. AFC.

  • Bengals are 3-1-1 ATS in their last 5 games in Week 1.
  • Bengals are 6-2 ATS in their last 8 games overall.
  • Home team is 4-1 ATS in their last 5 meetings.
  • Bengals are 1-4 ATS in their last 5 meetings in Indianapolis.

Buffalo Bills at Baltimore Ravens (-6, 41)

Oddsmakers are expecting this one to be a low-scoring affair.

  • Bills are 4-0 ATS in their last 4 games in September.
  • Bills are 4-1 ATS in their last 5 games in Week 1.
  • Bills are 4-1 ATS in their last 5 games overall.
  • Ravens are 7-3 ATS in their last 10 games in Week 1.

Jacksonville Jaguars at New York Giants (+3, 43.5)

It’s Leonard Fournette vs. Saquon Barkley!

  • Jaguars are 9-4 ATS in their last 13 road games.
  • Giants are 2-5 ATS in their last 7 games in Week 1.
  • Giants are 1-4 ATS in their last 5 games in September.

Tampa Bay Buccaneers at New Orleans Saints (-9.5, 49.5)

Drew Brees will be the best quarterback on the field in this one!

  • Buccaneers are 4-10 ATS in their last 14 games in September.
  • Buccaneers are 3-8 ATS in their last 11 games in Week 1.
  • Saints are 13-5 ATS in their last 18 vs. NFC South.

Houston Texans at New England Patriots (-6.5, 51)

Deshaun Watson and J.J. Watt versus Tom Brady and Gronk. It doesn’t get much better!

  • Texans are 5-2 ATS in their last 7 games in September.
  • Patriots are 21-7 ATS in their last 28 vs. AFC.
  • Patriots are 6-2 ATS in their last 8 games in September.

Tennessee Titans at Miami Dolphins (+2.5, 45)

I’ll take Tennessee’s Marcus Mariota over Miami’s Ryan Tannehill every time.

  • Titans are 4-0 ATS in their last 4 games on grass.
  • Titans are 4-1 ATS in their last 5 games overall.
  • Dolphins are 4-0 ATS in their last 4 games in Week 1.

Kansas City Chiefs at Los Angeles Chargers (-3, 47.5)

The Chargers have Super Bowl hopes, but the trends say the Chiefs are the pick to cover.

  • Road team is 5-1 ATS in their last 6 meetings.
  • Chiefs are 7-2 ATS in their last 9 meetings.

Seattle Seahawks at Denver Broncos (-2, 42)

It suddenly seems like a long time ago these two met in the Super Bowl.

  • Seahawks are 4-1-1 ATS in their last 6 road games.
  • Seahawks are 2-5 ATS in their last 7 games in Week 1.
  • Broncos are 1-4 ATS in their last 5 home games.
  • Broncos are 2-10 ATS in their last 12 games overall.

Dallas Cowboys at Carolina Panthers (-2.5, 45)

Cam Newton will be fired up for this regular season opener!

  • Cowboys are 5-1-1 ATS in their last 7 road games.
  • Cowboys are 4-1 ATS in their last 5 games in September.
  • Panthers are 4-1 ATS in their last 5 home games.
  • Panthers are 5-2 ATS in their last 7 games on grass.
  • Panthers are 7-3 ATS in their last 10 games overall.

Washington Redskins at Arizona Cardinals (Pk, 44)

Alex Smith and Steve Wilks make their respective debuts in this one.

  • Redskins are 2-5 ATS in their last 7 road games.
  • Redskins are 0-5 ATS in their last 5 games in Week 1.
  • Cardinals are 4-1-1 ATS in their last 6 home games.
  • Cardinals are 5-2-1 ATS in their last 8 games on grass.
  • Cardinals are 0-4 ATS in their last 4 games in September.

Chicago Bears at Green Bay Packers (-8, 47.5)

Aaron Rodgers is back at full strength while Matt Nagy makes his debut for Chicago.

  • Bears are 5-11 ATS in their last 16 road games.
  • Bears are 1-3-1 ATS in their last 5 games in Week 1.
  • Packers are 8-3 ATS in their last 11 games in Week 1.
  • Packers are 8-3 ATS in their last 11 games in September.

Monday, Sept. 10, 2018

New York Jets at Detroit Lions (-6.5, 44

The Jets could surprise this season. Matt Patricia makes his debut for Detroit.

  • Jets are 9-4-1 ATS in their last 14 games overall.
  • Jets are 2-5 ATS in their last 7 games in September.
  • Lions are 5-1 ATS in their last 6 Monday games.
  • Lions are 4-1 ATS in their last 5 games in Week 1.

Los Angeles Rams at Oakland (+3, 49.5)

Jon Gruden is back with the Raiders, but its its the Los Angeles Rams that have legitimate Super Bowl hopes.

  • Rams are 5-2 ATS in their last 7 road games.
  • Raiders are 3-9-2 ATS in their last 14 games overall.