Six College Football Playoff fields have featured at least one of Ohio State or Notre Dame, so there’s a lot riding on Saturday’s best non-conference matchup at 7:30 p.m. ET. According to SportsLine, the visiting No. 6 Buckeyes are favored by -3 points against the visiting No. 9 Fighting Irish.

Other notable Week 4 college football lines include No. 13 Alabama (-7) vs. No. 15 Ole Miss (3:30 p.m. ET, CBS), No. 4 Florida State (-2) vs. Clemson, No. 7 Penn State (-14.5) vs. No. 24 Iowa (7:30 p.m. ET, CBS), and No. 10 Oregon (-21) against. Deion Sanders and No. 19 Colorado. Before making any Week 4 college football picks on those or other games, check out Barrett Sallee’s top Week 4 college football expert picks, predictions, and best bets.

Sallee is a true insider: a CBS Sports analyst, SiriusXM broadcaster, Heisman voter, and one of the top CBS Sports analysts when it comes to picking games against the spread. He joined SportsLine in 2017 and has consistently produced his three best college football picks to members. He swept his SportsLine subscribers’ Week 3 best bets, hitting Over 48.5 in FSU-Boston College, Under 59 in Tennessee vs. Florida, and Washington -16 vs. Michigan State, all with plenty to spare.

He is now focusing on Week 4 college football odds and is sharing his top three best bets over at SportsLine. If you combine them, you may get a 6-1 return. SportsLine has his top college football picks.

Week 4 expert college football predictions

No. 8 Washington (-21.5) to cover the three-point spread against California in a Pac-12 kickoff at Husky Stadium at 10:30 p.m. ET is one of Sallee’s finest Week 4 college football choices.

The first thing that comes to mind when you think of the Huskies is offensive. They’ve amassed eye-popping pass stats, with Heisman hopeful Michael Penix Jr. collecting 400 yards through the air in all three games. In a 41-7 victory over Michigan State in Week 3, he was 27 of 35 for 473 yards, four touchdowns, and no interceptions.

Sallee is impressed with what he’s seen on that side of the ball, but he believes it’s Washington’s defense, which allows just 12 points per game, that distinguishes this team. “Will Cal be able to keep up in a track meet?” Nope. “Not against this defense, and certainly not at Husky Stadium,” Sallee told SportsLine. Visit SportsLine to see what other picks Sallee likes.

How to Make College Football Picks for Week 4

Sallee has also identified two more college football options he loves, including an underdog racing away late in a game where “the wrong team is favored.” His picks are only available on SportsLine.

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